In the evening, before bedtime, apply a small amount (about the size of a pea) of cream to clean, dry skin following your dermatologist's instructions. Avoid the eye area. Leave the cream on overnight. If desired, you can mix the cream with your regular moisturizer when applying to your face. When combining with other prescription skincare medications, ensure a minimum of 12 hours between applications, or as directed by your dermatologist.

Please note that Vanish contains ingredients that may increase your skin's sensitivity to the sun, making it more prone to sunburn. To prevent sunburn, it is important to use sunscreen, wear protective clothing, and limit sun exposure while using this product and for one week after discontinuing use.